Photochemical Intermolecular [3σ + 2σ]-Cycloaddition for the Construction of Aminobicyclo[3.1.1]heptanes.

Y, Zheng; W, Huang; RK, Dhungana; A, Granados; S, Keess; M, Makvandi; GA, Molander

doi:10.1021/jacs.2c11501

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Photochemical Intermolecular [3σ + 2σ]-Cycloaddition for the Construction of Aminobicyclo[3.1.1]heptanes.

Shared by NobleBlocks on Dec 15, 2022 • 12:00 AM UTC

Authors:

Zheng Y

Huang W

Dhungana RK

Abstract

The development of synthetic strategies for the preparation of bioisosteric compounds is a demanding undertaking in medicinal chemistry. Numerous strategies have been developed for the synthesis of bicyclo[1.1.1]pentanes (BCPs), bridge-substituted BCPs, and bicyclo[2.1.1]hexanes. However, progress o...

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