Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study.

Takata, Saori; Morikawa, Kei; Tanaka, Hisashi; Itani, Hidetoshi; Ishihara, Masashi; Horiuchi, Kazuya; Kato, Yasuhiro; Ikemura, Shinnosuke; Nakagawa, Hideyuki; Nakahara, Yoshiro; Seki, Yoshitaka; Bessho, Akihiro; Takahashi, Nobumasa; Hayashi, Kentaro; Endo, Takeo; Takeyama, Kiyoshi; Maekura, Toshiya; Takigawa, Nagio; Kawase, Akikazu; Endoh, Makoto; Nemoto, Kenji; Kishi, Kazuma; Soejima, Kenzo; Okuma, Yusuke; Yoshimura, Kenichi; Saigusa, Daisuke; Kanai, Yae; Ueda, Koji; Togashi, Akira; Matsutani, Noriyuki; Seki, Nobuhiko

doi:10.1177/17588359231177021

Public

Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study.

Shared by NobleBlocks on Jan 1, 2023 • 12:00 AM UTC

Authors:

Saori Takata

Kei Morikawa

Hisashi Tanaka

Abstract

Background: The exosome-focused translational research for afatinib (EXTRA) study is the first trial to identify novel predictive biomarkers for longer treatment efficacy of afatinib in patients with epidermal growth factor receptor (EGFR) mutation-positive nonsmall cell lung cancer (NSCLC) via a co...

Subject

EGFR–TKI

afatinib

biomarker

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