Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen

Peyrl, Andreas; Chocholous, Monika; Sabel, Magnus; Lassaletta, Alvaro; Sterba, Jaroslav; Leblond, Pierre; Nysom, Karsten; Torsvik, Ingrid; N. Chi, Susan; Perwein, Thomas; Jones, Neil; Holm, Stefan; Nyman, Per; Mörse, Helena; Öberg, Anders; Weiler-Wichtl, Liesa; Leiss, Ulrike; Haberler, Christine; T. Schmook, Maresa; Mayr, Lisa; Dieckmann, Karin; Kool, Marcel; Gojo, Johannes; A. Azizi, Amedeo; André, Nicolas; Kieran, Mark; Slavc, Irene

doi:10.1001/jamaoncol.2023.4437

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Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen

Shared by NobleBlocks on Dec 1, 2023 • 12:00 AM UTC

Authors:

Andreas Peyrl

Monika Chocholous

Magnus Sabel

Abstract

Importance Medulloblastoma recurrence in patients who have previously received irradiation has a dismal prognosis and lacks a standard salvage regimen. Objective To evaluate the response rate of pediatric patients with medulloblastoma recurrence using an antiangiogenic metronomic combinatorial appro...

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