Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation.

Li, Fan; Gallego, Jazlyn; N Tirko, Natasha; Greaser, Jenna; Bashe, Derek; Patel, Rudra; Shaker, Eric; E Van Valkenburg, Grace; S Alsubhi, Alanoud; Wellman, Steven; Singh, Vanshika; Garcia Padill, Camila; W Gheres, Kyle; Bagwell, Roger; Mulvihill, Maureen; D Y Kozai, Takashi

doi:10.1101/2023.12.05.570162

Public

Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation.

Shared by NobleBlocks on Dec 7, 2023 • 12:00 AM UTC

Authors:

Fan Li

Jazlyn Gallego

Natasha N Tirko

Abstract

Microglia are important players in surveillance and repair of the brain. Their activation mediates neuroinflammation caused by intracortical microelectrode implantation, which impedes the application of intracortical brain-computer interfaces (BCIs). While low-intensity pulsed ultrasound stimulation...

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