Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity

J. Aronne, Louis; Sattar, Naveed; B. Horn, Deborah; E. Bays, Harold; Wharton, Sean; Lin, Wen-Yuan; N. Ahmad, Nadia; Zhang, Shuyu; Liao, Ran; C. Bunck, Mathijs; Jouravskaya, Irina; A. Murphy, Madhumita; Investigators, SURMOUNT-4; O Fretes, José; J Coronel, Maria; L Gutnisky, Lucas; D Frechtel, Gustavo; Gelersztein, Elizabeth; Aizenberg, Diego; Maldonado, Natacha; Pereira, Márcio; G Santos, Queulla; Calil Salim, Camila; H Canani, Luis; Halpern, Bruno; AT Russo, Luis; Bodart, Joselita; V Neto, Danilo; Augusto, Gustavo; Leite, Silmara; Yang, Yi-Ching; Lin, Wen-Yuan; Huang, Chien-Ning; Huang, Kuo-Chin; Fitz-Patrick, David; HT Pau, Cindy; D Toth, Phillip; H Freeman, George; F Gardner, Donald; G Wynne, Alan; Loy, Juan; B Horn, Deborah; K Mehra, Purvi; Layle, Stacey; H Bergthold, James; de Souza, Jose; K Nadar, Venkatesh; R Albizu Angulo, Gustavo; R Cohen, Kenneth; R Smith, Timothy; J Aronne, Louis; Vaughn, Michael; A Alcantara-Gonzalez, Altagracia; B Forman, Seth; M Agaiby, John; A Geller, Steven; J Fraser, Neil; A Jenders, Robert; M Barbel-Johnson, Kim; K Mayfield, Ronald; D Vance, Carl; T Prier, Kevin; V Murray, Alexander; J Lillestol, Michael; S Denham, Douglas; Y Park, Jean; J Klein, Eric; E Bays, Harold; Philis-Tsimikas, Athena; E Bressler, Peter; CH Reed, John; Aslam, Shamaila; Rosenstock, Julio; P Frias, Juan; J Klaff, Leslie; Brazg, Ronald; Gomez-Cuellar, Martha; Connery, Lisa; T Van, Joanna; Selam, Jean-Louis; Kim, John; Blake, Dwight; Gabriel, John; Arora, Samir; J McCartney, Michael; K Solano, Royce; K Brodie, Steven; P Nardandrea, John

doi:10.1001/jama.2023.24945

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Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity

Shared by NobleBlocks on Jan 2, 2024 • 12:00 AM UTC

Authors:

Louis J. Aronne

Naveed Sattar

Deborah B. Horn

Abstract

Importance The effect of continued treatment with tirzepatide on maintaining initial weight reduction is unknown. Objective To assess the effect of tirzepatide, with diet and physical activity, on the maintenance of weight reduction. Design, Setting, and Participants This phase 3, randomized withdra...

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