T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time.

Ravishankar, Shashidhar; M H Towlerton, Andrea; L Tiamiyu, Iyabode; Mooka, Peter; Nankoma, Janet; Kafeero, James; Mubiru, Dennis; Sekitene, Semei; D Aicher, Lauri; P Miller, Chris; G Coffey, David; Okoche, Lazarus; Atwinirembabazi, Prisca; Okonye, Joseph; White, Jessica; M Koelle, David; Jing, Lichen; T Phipps, Warren; H Warren, Edus

doi:10.1101/2024.02.06.579223

Public

T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time.

Shared by NobleBlocks on Feb 15, 2025 • 12:00 AM UTC

Authors:

Shashidhar Ravishankar

Andrea M H Towlerton

Iyabode L Tiamiyu

Abstract

Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS), which causes significant morbidity and mortality worldwide, particularly in people living with HIV (PLWH) and in sub-Saharan Africa where KSHV seroprevalence is high. Postulating that T-cells specific for KSH...

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