Characteristics of discordance between amyloid positron emission tomography and plasma amyloid-β 42/40 positivity.

Pyun, Jung-Min; Ho Park, Young; Chul Youn, Young; Ju Kang, Min; Hwan Shim, Kyu; Jang, Jae-Won; You, Jihwan; Nho, Kwangsik; Kim, SangYun; Disease Neuroimaging Initiative, Alzheimer’s

doi:10.1038/s41398-024-02766-6

Public

Characteristics of discordance between amyloid positron emission tomography and plasma amyloid-β 42/40 positivity.

Shared by NobleBlocks on Feb 10, 2024 • 12:00 AM UTC

Authors:

Jung-Min Pyun

Young Ho Park

Young Chul Youn

Abstract

Various plasma biomarkers for amyloid-β (Aβ) have shown high predictability of amyloid PET positivity. However, the characteristics of discordance between amyloid PET and plasma Aβ42/40 positivity are poorly understood. Thorough interpretation of discordant cases is vital as Aβ plasma biomarker is i...

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