CAR-T cell-derived exosomes: a new perspective for cancer therapy

Sani, Farnaz; Shojaei, Shabnam; Amirhossein Tabatabaei, Seyed; Khorraminejad‐Shirazi, Mohammadhossein; Latifi, Mona; Sani, Mahsa; Azarpira, Negar

doi:10.1186/s13287-024-03783-4

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CAR-T cell-derived exosomes: a new perspective for cancer therapy

Published in Stem Cell Research & Therapy • Jun 18, 2024

Authors:

Farnaz Sani

Shabnam Shojaei

Seyed Amirhossein Tabatabaei

Abstract

Chimeric antigen receptor (CAR)-T cell adoptive immunotherapy is a promising cancer treatment that uses genetically engineered T cells to attack tumors. However, this therapy can have some adverse effects. CAR-T cell-derived exosomes are a potential alternative to CAR-T cells that may overcome some ...

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Open Access

Subject

Microvesicles

Chimeric antigen receptor

Cell therapy

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