Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted

Reina-Campos, Miguel; Monell, Alexander; Ferry, Amir; Luna, Vida; P. Cheung, Kitty; Galletti, Giovanni; E. Scharping, Nicole; K. Takehara, Kennidy; Quon, Sara; P. Challita, Peter; Boland, Brigid; Hsuan Lin, Yun; H. Wong, William; S. Indralingam, Cynthia; Neadeau, Hayley; Alarcón, Suzie; W. Yeo, Gene; T. Chang, John; Heeg, Maximilian; W. Goldrath, Ananda

doi:10.1038/s41586-024-08466-x

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Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted

Shared by NobleBlocks on Jan 22, 2025 • 12:00 AM UTC

Authors:

Miguel Reina-Campos

Alexander Monell

Amir Ferry

Abstract

Abstract Tissue-resident memory CD8 T (T RM ) cells provide protection from infection at barrier sites. In the small intestine, T RM cells are found in at least two distinct subpopulations: one with higher expression of effector molecules and another with greater memory potential 1 . However, the or...

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