Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome.

Ali, Sadaf; Zhang, Qianwen; Anwunah, Ijeoma; Baig, Shanat; da Silva Xavier, Gabriela; Dawson, Charlotte; Dassie, Francesca; Tang, Yijun; Wang, Libo; Chang, Guoying; Gleeson, Paul; T Warfield, Adrian; Paisey, Richard; G Barrett, Timothy; Maffei, Pietro; Wang, Xiumin; Homer, Victoria; Kershaw, Melanie; Geberhiwot, Tarekegn

doi:10.1210/clinem/dgaf356

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Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome.

Shared by NobleBlocks on Dec 18, 2025 • 12:00 AM UTC

Authors:

Sadaf Ali

Qianwen Zhang

Ijeoma Anwunah

Abstract

CONTEXT: Alström syndrome (AS) has been extensively studied for its multisystem organ manifestations. Primary gonadal failure is well described in humans, but little is known about the intricacies of puberty and true incidence of hypogonadism within this population. OBJECTIVE: We aimed to define the...

Subject

Alström syndrome

hypogonadism

male infertility

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