Objective responses and survival outcomes by grade 3-4 neutropenia in refractory metastatic colorectal cancer treated with trifluridine/tipiracil: Real-world evidence from the ReTrITA study.

Signorelli, Carlo; Basso, Michele; Alessandra Calegari, Maria; Passardi, Alessandro; Gallio, Chiara; Angotti, Lorenzo; Valeria Zurlo, Ina; Dell'Aquila, Emanuela; Gemma, Donatello; Cristiano Corsi, Domenico; Emiliani, Alessandra; Arrivi, Giulia; Zoratto, Federica; Santamaria, Fiorenza; Dettori, Manuela; Cosimati, Antonella; Saltarelli, Rosa; Minelli, Alessandro; Lucci-Cordisco, Emanuela; Giovanni Chilelli, Mario

doi:10.1200/jco.2026.44.16_suppl.e15611

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Objective responses and survival outcomes by grade 3-4 neutropenia in refractory metastatic colorectal cancer treated with trifluridine/tipiracil: Real-world evidence from the ReTrITA study.

Shared by NobleBlocks on Jun 1, 2026 • 12:00 AM UTC

Authors:

Carlo Signorelli

Michele Basso

Maria Alessandra Calegari

Abstract

e15611 Background: In refractory metastatic colorectal cancer (mCRC) treated with trifluridine/tipiracil (T), treatment-related neutropenia has been associated with improved survival. Whether this benefit is linked to objective response patterns in real-world practice remains unclear. This sub-analy...

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