Spectroscopic analysis on the binding interaction of biologically active pyrimidine derivative with bovine serum albumin.

VD, Suryawanshi; LS, Walekar; AH, Gore; PV, Anbhule; GB, Kolekar

doi:10.1016/j.jpha.2015.07.001

Public

Spectroscopic analysis on the binding interaction of biologically active pyrimidine derivative with bovine serum albumin.

Shared by NobleBlocks on Jul 15, 2015 • 12:00 AM UTC

Authors:

Suryawanshi VD

Walekar LS

Gore AH

Abstract

A biologically active antibacterial reagent<b>,</b> 2-amino-6-hydroxy-4-(4-N, N-dimethylaminophenyl)-pyrimidine-5-carbonitrile (AHDMAPPC), was synthesized. It was employed to investigate the binding interaction with the bovine serum albumin (BSA) in detail using different spectroscopic methods. It e...

Subject

Bovine serum albumin

Fluorescence spectroscopy

fluorescence resonance energy transfer (FRET)

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